Home Resource Centre Forthcoming Events About the Site

  • Frequency and Causes of Lipemia Interference of 
    Clinical Chemistry Laboratory Tests. S. Mainali, et al. Practical Lab Med 2017.
  • Preana
    lytical quality improvement: In pursuit of harmony. On behalf of European Federation for Clinical Chemistry and Laboratory Medicine (EFLM) Working group for Preanalytical Phase. Lippi G, et al. Clin Chem Lab Med 2015.
  • Quality management of the preanalytical phase: impact of lithium heparin vacuum tube changes on clinical chemistry tests. Oliveira G, et al. Accreditation and Quality Assurance, 2013.
  • Preanalytical quality in clinical chemistry laboratory. Ahmad M, et al. Clinical Laboratory, 2013.
  • Effects of blood collection tubes on the incidence of artifactual hyperkalemia on patient samples from an outreach clinic. Babic N, Zibrat S et al. Clinical Chimica Acta 2012.
  • Time dependent stability of 22 analytes in lithium plasma specimens stored at refrigerator temperature for up to 4 days. Van Vrancken M, Briscoe D et al. Lab Medicine 2012.
  • Evaluating preanalytical effects on immunoassays. Malone B. Clinicacl Laboratory Strategies 2012.
  • Plasma concentrations but serum concentrations of brain derived neurotrophic factor are related to proinflammatory cytokines in patients undergoing major abdominal surgery. Chimienti G, Mezzapesa A, Rotelli MT, Lupo L & Pepe G. Clinical Biochemistry 2012.
  • The effects of freeze thaw on B trace protein and B2-microglobulin assays after long term sample storage. Juraschek SP, Coresh J, Inker L, Rynders GP, Eckfeldt J & Selvin E. Clinical Biochemistry 2012.
  • Long-term stability of biochemical markers in pediatric serum specimens stored at -800C: A CALIPER substudy. Brinc D, Chan MK, Venner A & Pasic M. Clinical Biochemistry 2012.
  • Evaluation of an abbreviated centrifugation protocol for chemistry testing. Holland L & DomBourian M. Laboratory Medicine 2011; 43(3): 78-81.
  • Effects of different centrifugation conditions on clinical chemistry and immunology test results. BMC Clinical Pathology 2011; 11(6).
  • The feasibility of using lithium heparin plasma from gel separator tube as a substitute for serum in clinical biochemical tests. Wei Y, Zhang C, Yang X & Ji M. Laboratory Medicine 2010; 41(4): 215-219.
  • Preanalytical stability of 25(OH)-Vitamin D3 in human blood or serum at room temperature: Solid as a rock. Wielders JP, Wijnberg FA. Clinical Chemistry 2009; 55(8): 1584-95.
  • Hyperleukocytosis: pseudohyperkalaemia and other biochemical abnormalities in hyperleukocytosis. Dimeski G & Bird R. Clin Chem Lab Med 2009; 47(7): 880-881.
  • Acidification of blood is superior to sodium fluoride alone as an inhibitor of glycolysis. Gambino R, Piscitelli J, Ackattupathil TA, Theriault JL, Andrin RD, Sanfilippo ML & Etienne M. Clinical Chemistry 2009; 55(5): 1019-1021.
  • Glycolysis inhibitors negatively bias blood glucose measurements: potential impact on the reported prevalence of diabetes mellitus. Waring WS, Evans LE & Kirkpatrick CT. J Clin Pathol 2007; 60: 820-923.
  • No influence of a butterfly device on routine coagulation assays and D-dimer measurement. Lippi G, Salvagno GL, Guidi GC. International Society on Thrombosis and Hemostasis 2004.
  • Stability of brain natriuretic peptide (BNP) in human blood samples. Shimizu H, Aono K, Masuta K, Asada H, Misaki A & Teraoka H. Clin Chim Acta 1999; 285: 169-172.
  • Stabilization of Homocysteine in unseparated blood over several days: A solution for epidemiological studies. Clark S, Youngman LD, Sullivan J, Peto R & Collins R. Clin Chem 2003; 49(3): 518-520.
  • Stability of common biochemical analytes in serum gel tubes subjected to various storage temperatures and times pre-centrifugation. Tanner M, Kent N, Smith B, Fletcher S & Lewer M. Annals of Clinical Biochemistry 2008; 45: 375-379.
  • A comparison of two different assays for determining S-100B in serum and urine. Hallén M, Carlhed R, Karlsson M, Hallgren T & Bergenheim M. Clin Chem Lab Med 2008; 46(7): 1025-1029.
  • Long-term stability of endogenous B-type natriuretic peptide after storage at -200C or -800C. Pereira M, Azevedo A, Severo M & Barros H. Clin Chem Lab Med 2008; 46(8): 1171-1174.
  • Can both EDTA and citrate plasma samples be used in measurements of fibrinogen and C-reactive protein concentrations? Skeppholm M, Wallen NH, Blomback M & Kallner A. Clin Chem Lab Med 2008; 46(8): 1175-1179.
  • Non-homogeneous separation of triglycerides, gamma-glutamyltransferase, C-reactive protein and lactate dehydrogenase after centrifugation of lithium-heparin tubes. Salvagno GL, Lippi G, Montagnana M, Brocco G & Guidi GC. Clin Chem Lab Med 2008; 46(8): 1180-1182.
  • Measurement of mycophenolic acid in plasma or serum by a commercial enzyme inhibition technique in comparison with a high performance liquid chromatography method. Bunch DR & Wang S. Clin Chem Lab Med 2008; 46(9): 1281-1284.
  • Comprehensive profiling of the human circulating endocannabinoid metabolome: clinical sampling and sample storage parameters. Wood JT, Williams JS, Pandarinathan L, Courville A, Keplinger MR, Janero DR, Vouros P, Makriyannis A & Lammi-Keefe CJ. Clin Chem Lab Med 2008; 46(9): 1289-1295.
  • Effects of delayed sample processing and freezing on serum concentrations of selected nutritional indicators. Drammeh BS, Schleicher RL, Pfeiffer CM, Jain RB, Zhang M & Nguyen PH. Clin Chem 2008; 54(11): 1883-1891.
  • Quality specifications for the  determination of Copper, Zinc, and Selenium in human serum or plasma: Evaluation of an approach based on biological and analytical variation. Arnaud J, Weber JP, Weykamp CW, Parsons PJ, Angerer J, Mairiaux E, Mazarrasa O, Valkonen S, Menditto A, Patriarca M & Taylor A. Clin Chem 2008; 54(11): 1892-1899.
  • Serum 25-OH Vitamin D2 and D3 are stable under exaggerated conditions. Lewis JG & Elder PA. Clin Chem 2008; 54(11): 1931-1932.
  • Spurious hyperkalaemia due to EDTA contamination: common and not always easy to identify. Cornes MP, Ford C & Gama R. Ann Clin Biocchem 2008; 45: 601-603.
  • Troponin revisited 2008: assay performance. Tate JR. Clin Chem Lab Med 2008; 46(11): 1489-1500.
  • Low testosterone and risk of premature death in older men: Analytical and preanalytical issues in measuring circulating testosterone. Platz EA. Clinical Chemistry 2008; 54(7): 1110-1112.
  • Effect of collection tube type and preanalytical handling on myeloperoxidase concentrations. Shih J, Datwyler SA, Hsu SC, Matias MS, Pacenti DP, Lueders C, Mueller C, Danne O & Möckel M. Clinical Chemistry 2008; 54(6): 1076-1079.
  • Choline in whole blood and plasma: sample preparation and stability. Yue B, Pattison E, Roberts WL, Rockwood AL, Danne O, Lueders C & Möckel M. Clinical Chemistry 2008; 54(3): 590-593.
  • Two-year stability of NT-proBNP in frozen samples using the Roche ELecsys system. Cauliez B, Guignery J, Marinier S, Mariau I & Lavoinne A. Ann Clin Biochem. 2008; 45: 318-319.
  • Investigating elevated potassium values. Baer DM, Ernst DJ, Willeford SI & Gambino R. Medical Laboratory Observer 2006; 24-31.
  • Effects of prolonged ambient storage of sodium fluoride/heparin specimens on plasma homocysteine. Scheidhauer R, Guessregen B, Hohl A & Arndt T. Clinical Chemistry 2005; 51(8): 1564-1565.
  • A comparison of IgG anti-rubella activity in frozen serum stored in primary gel separation tubes or secondary tubes. Ellis V, Charlett A & Bendall R. J Clin Pathol 2004; 57(7): 104-106.
  • Suitability of frozen serum stored on gel separator primary sampling tubes for serological testing. Roosa-Fraile M, Sampedro A, Rodríguez-Granger J, Camacho E & Manrique E. Clin Diagn Lab Immunol. 2004; 11(1): 219-21.
  • Transport and temperature effects on measurement of serum and plasma potassium. Seamark D, Backhouse S, Barber P, Hichens J, Salzmann M, Powell R. J R Soc Med. 1999; 92(7): 339-41.  
  • Chemistry specimen acceptability: a College of American Pathologists Q-Probes study of 453 laboratories. Jones BA, Calam RR & Howanitz PJ. Arch Pathol Lab Med 1997; 121: 19-26.
  • Storage of whole blood: Effect of temperature on the measured concentration of analytes in serum. Rehak NN & Chiang BT. Clinical Chemistry 1988; 34(10): 2111-2114.
  • Lithium heparinised blood-collection tubes give falsely low albumin results with an automated bromcresol green method in haemodialysis patients. Meng QH & Krahn J. Clin Chem Lab Med 2008; 46(3): 396-400.
  • Different biological matrices (serum and plasma) utilization in consolidation processes: evaluation of seven Access immunoassays. Vignati G, Chiecchio A, Osnaghi B, Giovanelli L & Meloncelli C. Clin Chem Lab Med 2008; 46(2): 264-270.
  • Delay in separating blood samples affects creatinine measurement using the Roche kinetic Jaffe method. Ford L & Berg J. Annals of Clinical Biochemistry 2008; 45: 83-87.
  • Clinical validation of a new blood collection tube for the accuracy of total homocysteine measurement by different methods. Bissé E, Epting T, Kögel G, Obeid R, Gempel K, Huzly D, Fuhrmann K, Rolinski B, Herrmann W & Wieland H. Clinical Biochemistry 2007; 40: 739-743.
  • Stability of plasma homocysteine, S-Adenosylmethionine, and S-Adenosylhomocysteine in EDTA, Acidic Citrate, and Primavette™ Collection Tubes. Letter to the editor. Hubner U, Schorr H, Geisel J & Herrmann W. Clinical Chemistry 2007; 53(12): 2217-2218.
  • Are changes in blood-ethanol concentration during storage analytically significant? Importance of method imprecision. Jones AW. Clin Chem Lab Med 2007; 45(10): 1299-1304.
  • Type B natriuretic peptide stability in frozen plasma. Letter to the editor. Daves M & Cemin R. Clin Chem Lab Med 2007; 45(9): 1257-1258.
  • A model for an uncertainty budget for Preanalytical Variables in Clinical Chemistry Analyses. Rynning M, Wentzel-Larsen T & Bolann BJ. Clinical Chemistry 2007; 53(7): 1343-1348.
  • The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Banfi G, Salvagno GL & Lippi G. Clin Chem Lab Med 2007; 45(5): 565-576. 
  • Stability of oleander extract and oleandrin in sera stored in plastic serum separator tubes. Dasgupta A & White D. Ann Clin Biochem 2007; 44: 485-487.
  • Monitoring glycaemic control: is there evidence for appropriate use of routine measurement of glycated haemoglobin? Salvagno GL, Lippi G, Targher G, Montagnana M & Guidi GC. Clin Chem Lab Med 2007; 45(8): 1065-1067.
  • Trace and toxic elemental testing in the clinical laboratory. Bornhorst JA & McMillin GA. Lab Medicine 2006; 37(11): 690-696.
  • Parathyroid hormone is more stable in EDTA plasma than in serum. Glendenning P, Laffer LLA, Weber HK, Musk AA & Vasikaran SD. Clinical Chemistry 2002; 48(5): 766-777.

Last modification on 20 March 2017

[spacer image]


Need an Article?  

All articles listed on this page can be found on any of the following websites:

Google Scholar:


HighWire Press:


Infotrieve Online:


Life Sciences Magazines:




Science Direct:


[spacer image]
[spacer image]